Treatments and Trials

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Updated: 2 hours 26 min ago

MD Anderson/Mayo or Peter MacCallum for treatment?

19 October 2019
Hi all,
My husband is just diagnosed with CLL with WBC at 49, Platelet at 77, enlarged spleen 20 cm and enlarged liver 17 cm. 70% lymphocytes in bone marrow. The FISH test is not available yet until next week so the treatment plan is also not available. But seem that he’s on Stage IV under RAI classification.
We are in country in Asia where hospital is not that good so I’d like to take my husband to either Australia or US for treatment So we are considering Peter MacCallum in Melbourne and MD...

Bone Marrow at 65% after 6 months Imbruvica and ^ months of Gazyva

18 October 2019
My question is centered on expectations and bone marrow results. What is the expected bone marrow cellularity after 8 months of Imbruvica and 6 months of Gazyva infusions? My bone bone marrow cellularity before initial treatment were at 95% and after now are at 65%. I was hoping for more of a obliteration than a reduction, but maybe my expectations were off.
My other tests all came back great, lymph nodes shrunk and no other cancer detectable with the PET scan. I understand that Imbruvica...

Treatment Options

14 October 2019
Hello, a newbie member here, but have been reading the posts for some time and appreciate all the info. Would be interested in getting a little feedback before deciding (this Friday) on my future path of treatment.
I was diagnosed with CLL in April 2017 and have since been on W&W. But with my WBC now about 130 along with some swelling in the neck, arm regions, spleen, etc., my oncologist has recommended me to begin treatment (mostly due to my "doubling time", I believe). I have been given two...

iwCLL 2019 | Five-year follow up of the UK CLL Forum ibrutinib data

23 September 2019
Dr Toby Eyre, MD, Oxford University Hospitals NHS Foundation Trust, Oxford, UK, discusses the UK chronic lymphocytic leukemia (CLL) forum study led by George Follows, Cambridge University Hospitals, Cambridge, UK, and the 5-year follow up data for ibrutinib in R/R CLL.
This interview took place at the 18th International Workshop on Chronic Lymphocytic Leukemia (iwCLL) Biennial Meeting, held in Edinburgh, UK....

CLL FCR update - 3 years on.

23 September 2019
Hello all CLL curios. I have just had my latest 6 monthly ‘Watch and Wait’ blood tests and Flair trial assessment 3 years on from commencement of FCR chemotherapy. As I was an avid reader and regular contributor of posts on the build up and during my Chemo - drawing great strength and support - I felt I owe it to the forum to offer hope and support for all going through, or waiting for CLL treatment. My bloods are now ‘boringly’ normal (with a Lymphocyte count of 0.6) and I am still, happily,...

CLL and Mayo Clinic EGCG Phase I and 2 trials (Pharmaceutical grade Polyphenon-E derived from Green Tea)

21 September 2019
I believe some research is in progress at the Mayo Clinic evaluating the effect of EGCG from green tea on CLL progression as it appears to slow down the disease development.